Jonathan Paredes and Orlando Duque leaped from 30 metres above the section of river, which forms the boundary between Zambia and Zimbabwe.
Both Paredes and Duque usually dive from between 26.5 and 28 metres in the Cliff Diving World Series.
Mexico's Paredes won a World Series event last year for the first time and was second at the High Diving World Cup.
Colombia's Duque has 13 world titles and two world records.
The falls are the world's biggest in combined depth and width - the 'sheet' - and are also known as Mosi-oa-Tunya, or The Smoke that Thunders. (Reuters)